Designing and engineering evolutionary robust genetic circuits

BACKGROUND: One problem with engineered genetic circuits in synthetic microbes is their stability over evolutionary time in the absence of selective pressure. Since design of a selective environment for maintaining function of a circuit will be unique to every circuit, general design principles are...

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Detalles Bibliográficos
Autores principales: Sleight, Sean C, Bartley, Bryan A, Lieviant, Jane A, Sauro, Herbert M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991278/
https://www.ncbi.nlm.nih.gov/pubmed/21040586
http://dx.doi.org/10.1186/1754-1611-4-12

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991278/
https://www.ncbi.nlm.nih.gov/pubmed/21040586
http://dx.doi.org/10.1186/1754-1611-4-12

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