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25-Hydroxycholesterol exerts both a cox-2-dependent transient proliferative effect and cox-2-independent cytotoxic effect on bovine endothelial cells in a time- and cell-type-dependent manner

BACKGROUND: 25-hydroxycholesterol (25-OHC) is a product of oxidation of dietary cholesterol present in human plasma. 25-OHC and other oxidized forms of cholesterol are implicated in modulating inflammatory responses involved in development of atherosclerosis and colon carcinogenesis. METHODS: Primar...

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Detalles Bibliográficos
Autores principales: Nguyen, Vicky PKH, Chen, Stephen H, Pizzuto, Katerina, Cantarutti, Alyssa, Terminesi, Alyssa, Mendonca, Cassandra, Dumont, Daniel J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991284/
https://www.ncbi.nlm.nih.gov/pubmed/21070649
http://dx.doi.org/10.1186/2040-2384-2-24