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25-Hydroxycholesterol exerts both a cox-2-dependent transient proliferative effect and cox-2-independent cytotoxic effect on bovine endothelial cells in a time- and cell-type-dependent manner
BACKGROUND: 25-hydroxycholesterol (25-OHC) is a product of oxidation of dietary cholesterol present in human plasma. 25-OHC and other oxidized forms of cholesterol are implicated in modulating inflammatory responses involved in development of atherosclerosis and colon carcinogenesis. METHODS: Primar...
Autores principales: | Nguyen, Vicky PKH, Chen, Stephen H, Pizzuto, Katerina, Cantarutti, Alyssa, Terminesi, Alyssa, Mendonca, Cassandra, Dumont, Daniel J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991284/ https://www.ncbi.nlm.nih.gov/pubmed/21070649 http://dx.doi.org/10.1186/2040-2384-2-24 |
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