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SNP-SNP interactions dominate the genetic architecture of candidate genes associated with left ventricular mass in african-americans of the GENOA study

BACKGROUND: Left ventricular mass (LVM) is a strong, independent predictor of heart disease incidence and mortality. LVM is a complex, quantitative trait with genetic and environmental risk factors. This research characterizes the genetic architecture of LVM in an African-American population by exam...

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Detalles Bibliográficos
Autores principales: Meyers, Kristin J, Chu, Jian, Mosley, Thomas H, Kardia, Sharon LR
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991303/
https://www.ncbi.nlm.nih.gov/pubmed/21067599
http://dx.doi.org/10.1186/1471-2350-11-160