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Overrepresentation of IL-17A and IL-22 Producing CD8 T Cells in Lesional Skin Suggests Their Involvement in the Pathogenesis of Psoriasis

BACKGROUND: Although recent studies indicate a crucial role for IL-17A and IL-22 producing T cells in the pathogenesis of psoriasis, limited information is available on their frequency and heterogeneity and their distribution in skin in situ. METHODOLOGY/PRINCIPAL FINDINGS: By spectral imaging analy...

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Detalles Bibliográficos
Autores principales: Res, Pieter C. M., Piskin, Gamze, de Boer, Onno J., van der Loos, Chris M., Teeling, Peter, Bos, Jan D., Teunissen, Marcel B. M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991333/
https://www.ncbi.nlm.nih.gov/pubmed/21124836
http://dx.doi.org/10.1371/journal.pone.0014108