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Overrepresentation of IL-17A and IL-22 Producing CD8 T Cells in Lesional Skin Suggests Their Involvement in the Pathogenesis of Psoriasis
BACKGROUND: Although recent studies indicate a crucial role for IL-17A and IL-22 producing T cells in the pathogenesis of psoriasis, limited information is available on their frequency and heterogeneity and their distribution in skin in situ. METHODOLOGY/PRINCIPAL FINDINGS: By spectral imaging analy...
Autores principales: | Res, Pieter C. M., Piskin, Gamze, de Boer, Onno J., van der Loos, Chris M., Teeling, Peter, Bos, Jan D., Teunissen, Marcel B. M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991333/ https://www.ncbi.nlm.nih.gov/pubmed/21124836 http://dx.doi.org/10.1371/journal.pone.0014108 |
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