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TGF-β Induces Surface LAP Expression on Murine CD4 T Cells Independent of Foxp3 Induction
BACKGROUND: It has been reported that human FOXP3(+) CD4 Tregs express GARP-anchored surface latency-associated peptide (LAP) after activation, based on the use of an anti-human LAP mAb. Murine CD4 Foxp3(+) Tregs have also been reported to express surface LAP, but these studies have been hampered by...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991360/ https://www.ncbi.nlm.nih.gov/pubmed/21124798 http://dx.doi.org/10.1371/journal.pone.0015523 |