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Tenascin-C promotes melanoma progression by maintaining the ABCB5-positive side population

Tenascin-C (TNC) is highly expressed in melanoma; however, little is known about its functions. Recent studies indicate that TNC plays a role within the stem cell niche. We hypothesized that TNC creates a specific environment for melanoma cells to exhibit a stem cell-like phenotype, driving tumor gr...

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Detalles Bibliográficos
Autores principales: Fukunaga-Kalabis, Mizuho, Martinez, Gabriela, Nguyen, Thierry-Thien K., Kim, Diana, Santiago-Walker, Ademi, Roesch, Alexander, Herlyn, Meenhard
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991494/
https://www.ncbi.nlm.nih.gov/pubmed/20729912
http://dx.doi.org/10.1038/onc.2010.350