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QTc interval prolongation by fexofenadine in healthy human volunteers and its correlation with plasma levels of fexofenadine: A demonstration of anticlockwise hysteresis

AIM: The study was designed to establish relationship between the plasma concentration and QTc interval prolonging effect of fexofenadine and demonstrate the phenomenon of anticlockwise hysteresis. MATERIALS AND METHODS: Six subjects were given fexofenadine 60 mg tablet orally under stable condition...

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Detalles Bibliográficos
Autores principales: Vyas, Falgun I., Prakash, Shiv, Singh, A.J.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991694/
https://www.ncbi.nlm.nih.gov/pubmed/21189907
http://dx.doi.org/10.4103/0253-7613.71919