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Genetic associations in type I interferon related pathways with autoimmunity

Type I interferons play an outstanding role in innate and adaptive immunity by enhancing functions of dendritic cells, inducing differentiation of monocytes, promoting immunoglobulin class switching in B cells and stimulating effector functions of T cells. The increased production of IFNα/β by plasm...

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Detalles Bibliográficos
Autores principales: Delgado-Vega, Angélica M, Alarcón-Riquelme, Marta E, Kozyrev, Sergey V
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991775/
https://www.ncbi.nlm.nih.gov/pubmed/20392289
http://dx.doi.org/10.1186/ar2883