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Genetic associations in type I interferon related pathways with autoimmunity
Type I interferons play an outstanding role in innate and adaptive immunity by enhancing functions of dendritic cells, inducing differentiation of monocytes, promoting immunoglobulin class switching in B cells and stimulating effector functions of T cells. The increased production of IFNα/β by plasm...
Autores principales: | Delgado-Vega, Angélica M, Alarcón-Riquelme, Marta E, Kozyrev, Sergey V |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991775/ https://www.ncbi.nlm.nih.gov/pubmed/20392289 http://dx.doi.org/10.1186/ar2883 |
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