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Potential role of IFNα in adult lupus

Patients with lupus have a continuous production of IFNα and display an increased expression of IFNα-regulated genes. The reason for the ongoing IFNα synthesis in these patients seems to be an activation of plasmacytoid dendritic cells (pDCs) by immune complexes (ICs), consisting of autoantibodies i...

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Detalles Bibliográficos
Autor principal: Rönnblom, Lars
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991776/
https://www.ncbi.nlm.nih.gov/pubmed/20392290
http://dx.doi.org/10.1186/ar2884