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Genetic defects of GDF6 in the zebrafish out of sight mutant and in human eye developmental anomalies

BACKGROUND: The size of the vertebrate eye and the retina is likely to be controlled at several stages of embryogenesis by mechanisms that affect cell cycle length as well as cell survival. A mutation in the zebrafish out of sight (out) locus results in a particularly severe reduction of eye size. T...

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Detalles Bibliográficos
Autores principales: den Hollander, Anneke I, Biyanwila, Janisha, Kovach, Peter, Bardakjian, Tanya, Traboulsi, Elias I, Ragge, Nicola K, Schneider, Adele, Malicki, Jarema
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992036/
https://www.ncbi.nlm.nih.gov/pubmed/21070663
http://dx.doi.org/10.1186/1471-2156-11-102