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Inhibition of core gene of HCV 3a genotype using synthetic and vector derived siRNAs
BACKGROUND: Hepatitis C virus (HCV) is a major causative agent of liver associated diseases throughout the world, with genotype 3a responsible for most of the cases in Pakistan. Due to the limited efficiency of current therapy, RNA interference (RNAi) a novel regulatory and powerful silencing approa...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992066/ https://www.ncbi.nlm.nih.gov/pubmed/21073745 http://dx.doi.org/10.1186/1743-422X-7-318 |