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Inhibition of core gene of HCV 3a genotype using synthetic and vector derived siRNAs

BACKGROUND: Hepatitis C virus (HCV) is a major causative agent of liver associated diseases throughout the world, with genotype 3a responsible for most of the cases in Pakistan. Due to the limited efficiency of current therapy, RNA interference (RNAi) a novel regulatory and powerful silencing approa...

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Detalles Bibliográficos
Autores principales: Khaliq, Saba, Jahan, Shah, Ijaz, Bushra, Ahmad, Waqar, Asad, Sultan, Pervaiz, Asim, Samreen, Baila, Khan, Mahwish, Hassan, Sajida
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992066/
https://www.ncbi.nlm.nih.gov/pubmed/21073745
http://dx.doi.org/10.1186/1743-422X-7-318