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Effects of anti-malarial drugs on the electrocardiographic QT interval modelled in the isolated perfused guinea pig heart system

BACKGROUND: Concern over the potential cardiotoxicity of anti-malarial drugs inducing a prolonged electrocardiographic QT interval has resulted in the almost complete withdrawal from the market of one anti-malarial drug - halofantrine. The effects on the QT interval of four anti-malarial drugs were...

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Detalles Bibliográficos
Autores principales: Kinoshita, Atsushi, Yamada, Harumi, Kotaki, Hajime, Kimura, Mikio
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992072/
https://www.ncbi.nlm.nih.gov/pubmed/21067575
http://dx.doi.org/10.1186/1475-2875-9-318