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Effects of anti-malarial drugs on the electrocardiographic QT interval modelled in the isolated perfused guinea pig heart system
BACKGROUND: Concern over the potential cardiotoxicity of anti-malarial drugs inducing a prolonged electrocardiographic QT interval has resulted in the almost complete withdrawal from the market of one anti-malarial drug - halofantrine. The effects on the QT interval of four anti-malarial drugs were...
Autores principales: | Kinoshita, Atsushi, Yamada, Harumi, Kotaki, Hajime, Kimura, Mikio |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992072/ https://www.ncbi.nlm.nih.gov/pubmed/21067575 http://dx.doi.org/10.1186/1475-2875-9-318 |
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