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ERK and JNK Activation is Essential for Oncogenic Transformation by v-Rel

v-Rel is the acutely oncogenic member of the NF-κB family of transcription factors. Infection with retroviruses expressing v-Rel rapidly induces fatal lymphomas in birds and transforms primary lymphocytes and fibroblasts in vitro. We have previously shown that AP-1 transcriptional activity contribut...

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Detalles Bibliográficos
Autores principales: Kralova, Jarmila, Sheely, Juliana I., Liss, Andrew S., Bose, Henry R.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992084/
https://www.ncbi.nlm.nih.gov/pubmed/20802521
http://dx.doi.org/10.1038/onc.2010.359