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Calreticulin Controls the Rate of Assembly of CD1d Molecules in the Endoplasmic Reticulum

CD1d is an MHC class I-like molecule comprised of a transmembrane glycoprotein (heavy chain) associated with β(2)-microglobulin (β(2)m) that presents lipid antigens to NKT cells. Initial folding of the heavy chain involves its glycan-dependent association with calreticulin (CRT), calnexin (CNX), and...

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Detalles Bibliográficos
Autores principales: Zhu, Yajuan, Zhang, Wei, Veerapen, Natacha, Besra, Gurdyal, Cresswell, Peter
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992262/
https://www.ncbi.nlm.nih.gov/pubmed/20861015
http://dx.doi.org/10.1074/jbc.M110.170530