SUMOylation of the GTPase Rac1 is required for optimal cell migration

The Rho-like GTPase Rac1 induces cytoskeletal rearrangements required for cell migration. Rac activity is regulated through a number of mechanisms, including control of nucleotide exchange and hydrolysis, regulation of subcellular localization, or modulation of protein expression levels1-3. Here, we...

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Detalles Bibliográficos
Autores principales: Castillo-Lluva, Sonia, Tatham, Michael H., Jones, Richard C., Jaffray, Ellis G., Edmondson, Ricky D., Hay, Ronald T., Malliri, Angeliki
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992316/
https://www.ncbi.nlm.nih.gov/pubmed/20935639
http://dx.doi.org/10.1038/ncb2112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992316/
https://www.ncbi.nlm.nih.gov/pubmed/20935639
http://dx.doi.org/10.1038/ncb2112

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