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Hypoxia-inducible factor regulates osteoclast-mediated bone resorption: role of angiopoietin-like 4

Hypoxia and the hypoxia-inducible factor (HIF) transcription factor regulate angiogenic-osteogenic coupling and osteoclast-mediated bone resorption. To determine how HIF might coordinate osteoclast and osteoblast function, we studied angiopoietin-like 4 (ANGPTL4), the top HIF target gene in an Illum...

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Detalles Bibliográficos
Autores principales: Knowles, Helen J., Cleton-Jansen, Anne-Marie, Korsching, Eberhard, Athanasou, Nicholas A.
Formato: Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992372/
https://www.ncbi.nlm.nih.gov/pubmed/20667978
http://dx.doi.org/10.1096/fj.10-162230