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Effects of pegylated G-CSF on immune cell number and function in patients with gynecological malignancies

BACKGROUND: Pegylated granulocyte colony-stimulating factor (G-CSF; pegfilgrastim) is a longer-acting form of G-CSF, whose effects on dendritic cell (DC) and regulatory T cell (Treg) mobilization, and on the in vivo and ex vivo release of immune modulating cytokines remain unexplored. METHODS: Twelv...

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Detalles Bibliográficos
Autores principales: Bonanno, Giuseppina, Procoli, Annabella, Mariotti, Andrea, Corallo, Maria, Perillo, Alessandro, Danese, Silvio, De Cristofaro, Raimondo, Scambia, Giovanni, Rutella, Sergio
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992497/
https://www.ncbi.nlm.nih.gov/pubmed/21062439
http://dx.doi.org/10.1186/1479-5876-8-114