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Nociceptor-expressed ephrin-B2 regulates inflammatory and neuropathic pain

BACKGROUND: EphB receptors and their ephrin-B ligands play an important role in nervous system development, as well as synapse formation and plasticity in the adult brain. Recent studies show that intrathecal treatment with EphB-receptor activator ephrinB2-Fc induced thermal hyperalgesia and mechani...

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Detalles Bibliográficos
Autores principales: Zhao, Jing, Yuan, Guanglu, Cendan, Cruz M, Nassar, Mohammed A, Lagerström, Malin C, Kullander, Klas, Gavazzi, Isabella, Wood, John N
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992507/
https://www.ncbi.nlm.nih.gov/pubmed/21059214
http://dx.doi.org/10.1186/1744-8069-6-77