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Antiproliferative and pro-apoptotic effects afforded by novel Src-kinase inhibitors in human neuroblastoma cells

BACKGROUND: Neuroblastoma (NB) is the second most common solid malignancy of childhood that usually undergoes rapid progression with a poor prognosis upon metastasis. The Src-family tyrosine kinases (SFKs) are a group of proteins involved in cancer development and invasiveness that seem to play an i...

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Detalles Bibliográficos
Autores principales: Navarra, Michele, Celano, Marilena, Maiuolo, Jessica, Schenone, Silvia, Botta, Maurizio, Angelucci, Adriano, Bramanti, Placido, Russo, Diego
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992519/
https://www.ncbi.nlm.nih.gov/pubmed/21050441
http://dx.doi.org/10.1186/1471-2407-10-602