Detection of copy number variation from array intensity and sequencing read depth using a stepwise Bayesian model

BACKGROUND: Copy number variants (CNVs) have been demonstrated to occur at a high frequency and are now widely believed to make a significant contribution to the phenotypic variation in human populations. Array-based comparative genomic hybridization (array-CGH) and newly developed read-depth approa...

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Detalles Bibliográficos
Autores principales: Zhang, Zhengdong D, Gerstein, Mark B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992546/
https://www.ncbi.nlm.nih.gov/pubmed/21034510
http://dx.doi.org/10.1186/1471-2105-11-539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992546/
https://www.ncbi.nlm.nih.gov/pubmed/21034510
http://dx.doi.org/10.1186/1471-2105-11-539

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