Novel Small Molecule Glucagon-Like Peptide-1 Receptor Agonist Stimulates Insulin Secretion in Rodents and From Human Islets

OBJECTIVE: The clinical effectiveness of parenterally-administered glucagon-like peptide-1 (GLP-1) mimetics to improve glucose control in patients suffering from type 2 diabetes strongly supports discovery pursuits aimed at identifying and developing orally active, small molecule GLP-1 receptor agon...

Descripción completa

Detalles Bibliográficos
Autores principales: Sloop, Kyle W., Willard, Francis S., Brenner, Martin B., Ficorilli, James, Valasek, Kathleen, Showalter, Aaron D., Farb, Thomas B., Cao, Julia X.C., Cox, Amy L., Michael, M. Dodson, Gutierrez Sanfeliciano, Sonia Maria, Tebbe, Mark J., Coghlan, Michael J.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Islet Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992771/
https://www.ncbi.nlm.nih.gov/pubmed/20823098
http://dx.doi.org/10.2337/db10-0689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992771/
https://www.ncbi.nlm.nih.gov/pubmed/20823098
http://dx.doi.org/10.2337/db10-0689

Ejemplares similares