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Effects of PNPLA3 on Liver Fat and Metabolic Profile in Hispanic Children and Adolescents

OBJECTIVE: A genome-wide study of adults identified a variant of PNPLA3 (rs738409) associated with ∼twofold higher liver fat. The purpose of this study was to examine the influence of PNPLA3 genotype on liver fat and other related metabolic outcomes in obese Hispanic children and adolescents. RESEAR...

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Detalles Bibliográficos
Autores principales: Goran, Michael I., Walker, Ryan, Le, Kim-Anne, Mahurkar, Swapna, Vikman, Susanna, Davis, Jaimie N., Spruijt-Metz, Donna, Weigensberg, Marc J., Allayee, Hooman
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992774/
https://www.ncbi.nlm.nih.gov/pubmed/20852027
http://dx.doi.org/10.2337/db10-0554