Apolipoprotein A-I Mimetic Peptides Prevent Atherosclerosis Development and Reduce Plaque Inflammation in a Murine Model of Diabetes

OBJECTIVE: To determine the effect of the apolipoprotein A-I (ApoA-I) mimetic peptide, D-4F, on atherosclerosis development in a pre-existing diabetic condition. RESEARCH DESIGN AND METHODS: We induced hyperglycemia in 6-week-old apoE(−/−) female mice using streptozotocin. Half of the diabetic apoE(...

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Detalles Bibliográficos
Autores principales: Morgantini, Cecilia, Imaizumi, Satoshi, Grijalva, Victor, Navab, Mohamad, Fogelman, Alan M., Reddy, Srinivasa T.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Pharmacology and Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992786/
https://www.ncbi.nlm.nih.gov/pubmed/20826564
http://dx.doi.org/10.2337/db10-0844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992786/
https://www.ncbi.nlm.nih.gov/pubmed/20826564
http://dx.doi.org/10.2337/db10-0844

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