Contribution of biotransformation enzymes to the development of renal injury and urothelial cancer caused by aristolochic acid: urgent questions, difficult answers

Ingestion of aristolochic acid (AA) is associated with the development of aristolochic acid nephropathy, which is characterized by chronic renal failure, tubulointerstitial fibrosis and urothelial cancer. AA may also cause a similar type of kidney fibrosis with malignant transformation of the urothe...

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Detalles Bibliográficos
Autores principales: Stiborová, Marie, Hudeček, Jiří, Frei, Eva, Schmeiser, Heinz H.
Formato: Texto
Lenguaje:English
Publicado: Slovak Toxicology Society SETOX 2008
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993473/
https://www.ncbi.nlm.nih.gov/pubmed/21218097
http://dx.doi.org/10.2478/v10102-010-0023-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993473/
https://www.ncbi.nlm.nih.gov/pubmed/21218097
http://dx.doi.org/10.2478/v10102-010-0023-1

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