Rat cytochromes P450 oxidize 3-aminobenzanthrone, a human metabolite of the carcinogenic environmental pollutant 3-nitrobenzanthrone

3-Aminobenzanthrone (3-ABA) is a human metabolite of carcinogenic 3-nitrobenzanthrone (3-NBA), which occurs in diesel exhaust and air pollution. Understanding which cytochrome P450 (CYP) enzymes are involved in metabolic activation and/or detoxication of this toxicant is important in the assessment...

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Detalles Bibliográficos
Autores principales: Mizerovská, Jana, Dračínská, Helena, Arlt, Volker M., Hudeček, Jiří, Hodek, Petr, Schmeiser, Heinz H, Frei, Eva, Stiborová, Marie
Formato: Texto
Lenguaje:English
Publicado: Slovak Toxicology Society SETOX 2008
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993481/
https://www.ncbi.nlm.nih.gov/pubmed/21218105
http://dx.doi.org/10.2478/v10102-010-0031-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993481/
https://www.ncbi.nlm.nih.gov/pubmed/21218105
http://dx.doi.org/10.2478/v10102-010-0031-1

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