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Experimental approaches to evaluate activities of cytochromes P450 3A

Cytochrome P450 (CYP) is a heme protein oxidizing various xenobiotics, as well as endogenous substrates. Understanding which CYP enzymes are involved in metabolic activation and/or detoxication of different compounds is important in the assessment of an individual's susceptibility to the toxic...

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Detalles Bibliográficos
Autores principales: Bořek-Dohalská, Lucie, Hodek, Petr, Hudeček, Jiří, Stiborová, Marie
Formato: Texto
Lenguaje:English
Publicado: Slovak Toxicology Society SETOX 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993482/
https://www.ncbi.nlm.nih.gov/pubmed/21218106
http://dx.doi.org/10.2478/v10102-010-0032-0