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Experimental approaches to evaluate activities of cytochromes P450 3A
Cytochrome P450 (CYP) is a heme protein oxidizing various xenobiotics, as well as endogenous substrates. Understanding which CYP enzymes are involved in metabolic activation and/or detoxication of different compounds is important in the assessment of an individual's susceptibility to the toxic...
Autores principales: | Bořek-Dohalská, Lucie, Hodek, Petr, Hudeček, Jiří, Stiborová, Marie |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Slovak Toxicology Society SETOX
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993482/ https://www.ncbi.nlm.nih.gov/pubmed/21218106 http://dx.doi.org/10.2478/v10102-010-0032-0 |
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