Oxidation of carcinogenic 2-nitroanisole by rat cytochromes P450 – similarity between human and rat enzymes

2-Nitroanisole (2-NA) is an important industrial pollutant and a potent carcinogen for rodents. Understanding which cytochrome P450 (CYP) enzymes are involved in its metabolism are important to assess an individual's susceptibility to this environmental carcinogen. The aim of this study was to...

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Detalles Bibliográficos
Autores principales: Svobodová, Martina, Dračínská, Helena, Martínková, Markéta, Hudeček, Jiří, Hodek, Petr, Frei, Eva, Stiborová, Marie
Formato: Texto
Lenguaje:English
Publicado: Slovak Toxicology Society SETOX 2008
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993485/
https://www.ncbi.nlm.nih.gov/pubmed/21218109
http://dx.doi.org/10.2478/v10102-010-0035-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993485/
https://www.ncbi.nlm.nih.gov/pubmed/21218109
http://dx.doi.org/10.2478/v10102-010-0035-x

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