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Oxidation of carcinogenic 2-nitroanisole by rat cytochromes P450 – similarity between human and rat enzymes
2-Nitroanisole (2-NA) is an important industrial pollutant and a potent carcinogen for rodents. Understanding which cytochrome P450 (CYP) enzymes are involved in its metabolism are important to assess an individual's susceptibility to this environmental carcinogen. The aim of this study was to...
Autores principales: | Svobodová, Martina, Dračínská, Helena, Martínková, Markéta, Hudeček, Jiří, Hodek, Petr, Frei, Eva, Stiborová, Marie |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Slovak Toxicology Society SETOX
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993485/ https://www.ncbi.nlm.nih.gov/pubmed/21218109 http://dx.doi.org/10.2478/v10102-010-0035-x |
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