The comparison of cytotoxicity of the anticancer drugs doxorubicin and ellipticine to human neuroblastoma cells

Ellipticine is an antineoplastic agent, whose mode of action is based mainly on DNA intercalation, inhibition of topoisomerase II and formation of covalent DNA adducts mediated by cytochromes P450 and peroxidases. Here, the cytotoxicity of ellipticine to human neuroblastoma derived cell lines IMR-32...

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Detalles Bibliográficos
Autores principales: Poljaková, Jitka, Eckschlager, Tomáš, Hřebačková, Jana, Hraběta, Jan, Stiborová, Marie
Formato: Texto
Lenguaje:English
Publicado: Slovak Toxicology Society SETOX 2008
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993486/
https://www.ncbi.nlm.nih.gov/pubmed/21218110
http://dx.doi.org/10.2478/v10102-010-0036-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993486/
https://www.ncbi.nlm.nih.gov/pubmed/21218110
http://dx.doi.org/10.2478/v10102-010-0036-9

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