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Modeling cardiac β-adrenergic signaling with normalized-Hill differential equations: comparison with a biochemical model
BACKGROUND: New approaches are needed for large-scale predictive modeling of cellular signaling networks. While mass action and enzyme kinetic approaches require extensive biochemical data, current logic-based approaches are used primarily for qualitative predictions and have lacked direct quantitat...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993667/ https://www.ncbi.nlm.nih.gov/pubmed/21087478 http://dx.doi.org/10.1186/1752-0509-4-157 |