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Construction of Metabolically Biotinylated Adenovirus with Deleted Fiber Knob as Targeting Vector

Gene delivery vectors based on adenovirus, particularly human adenovirus serotype 5 (hAd5) have great potential for the treatment of variety of diseases. However, the tropism of hAd5 needs to be modified to achieve tissue- or cell- specific therapies for the successful application of this vector sys...

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Detalles Bibliográficos
Autores principales: Liu, Yanzheng, Valadon, Philippe, Schnitzer, Jan E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993673/
https://www.ncbi.nlm.nih.gov/pubmed/21073735
http://dx.doi.org/10.1186/1743-422X-7-316