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The two most common histological subtypes of malignant germ cell tumour are distinguished by global microRNA profiles, associated with differential transcription factor expression

BACKGROUND: We hypothesised that differences in microRNA expression profiles contribute to the contrasting natural history and clinical outcome of the two most common types of malignant germ cell tumour (GCT), yolk sac tumours (YSTs) and germinomas. RESULTS: By direct comparison, using microarray da...

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Detalles Bibliográficos
Autores principales: Murray, Matthew J, Saini, Harpreet K, van Dongen, Stijn, Palmer, Roger D, Muralidhar, Balaji, Pett, Mark R, Piipari, Matias, Thornton, Claire M, Nicholson, James C, Enright, Anton J, Coleman, Nicholas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993676/
https://www.ncbi.nlm.nih.gov/pubmed/21059207
http://dx.doi.org/10.1186/1476-4598-9-290