Hippocampal FGF-2 and BDNF overexpression attenuates epileptogenesis-associated neuroinflammation and reduces spontaneous recurrent seizures

Under certain experimental conditions, neurotrophic factors may reduce epileptogenesis. We have previously reported that local, intrahippocampal supplementation of fibroblast growth factor-2 (FGF-2) and brain-derived neurotrophic factor (BDNF) increases neurogenesis, reduces neuronal loss, and reduc...

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Detalles Bibliográficos
Autores principales: Bovolenta, Roberta, Zucchini, Silvia, Paradiso, Beatrice, Rodi, Donata, Merigo, Flavia, Mora, Graciela Navarro, Osculati, Francesco, Berto, Elena, Marconi, Peggy, Marzola, Andrea, Fabene, Paolo F, Simonato, Michele
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993685/
https://www.ncbi.nlm.nih.gov/pubmed/21087489
http://dx.doi.org/10.1186/1742-2094-7-81

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993685/
https://www.ncbi.nlm.nih.gov/pubmed/21087489
http://dx.doi.org/10.1186/1742-2094-7-81

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