Cell death by the quinoxaline dioxide DCQ in human colon cancer cells is enhanced under hypoxia and is independent of p53 and p21

INTRODUCTION: We have shown that the radio sensitizer DCQ enhances sensitivity of HCT116 human colon cancer cells to hypoxia. However, it is not known whether the p53 or p21 genes influence cellular response to DCQ. In this study, we used HCT116 that are either wildtype for p53 and p21, null for p53...

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Detalles Bibliográficos
Autores principales: El-Khatib, Mona, Geara, Fady, Haddadin, Makhluf J, Gali-Muhtasib, Hala
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993715/
https://www.ncbi.nlm.nih.gov/pubmed/21078189
http://dx.doi.org/10.1186/1748-717X-5-107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993715/
https://www.ncbi.nlm.nih.gov/pubmed/21078189
http://dx.doi.org/10.1186/1748-717X-5-107

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