Differential Modulation of Keratin Expression by Sulforaphane Occurs via Nrf2-dependent and -independent Pathways in Skin Epithelia

Treatment with the natural chemical sulforaphane (SF) ameliorates skin blistering in keratin 14 (K14)-deficient mice, correlating with the induction of K16 and K17 in the basal layer of epidermis (Kerns et al., PNAS 104:14460, 2007). Here we address the basis for the SF-mediated K16 and K17 inductio...

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Detalles Bibliográficos
Autores principales: Kerns, Michelle, DePianto, Daryle, Yamamoto, Masayuki, Coulombe, Pierre A.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993737/
https://www.ncbi.nlm.nih.gov/pubmed/20926689
http://dx.doi.org/10.1091/mbc.E10-02-0153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993737/
https://www.ncbi.nlm.nih.gov/pubmed/20926689
http://dx.doi.org/10.1091/mbc.E10-02-0153

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