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Differential Modulation of Keratin Expression by Sulforaphane Occurs via Nrf2-dependent and -independent Pathways in Skin Epithelia
Treatment with the natural chemical sulforaphane (SF) ameliorates skin blistering in keratin 14 (K14)-deficient mice, correlating with the induction of K16 and K17 in the basal layer of epidermis (Kerns et al., PNAS 104:14460, 2007). Here we address the basis for the SF-mediated K16 and K17 inductio...
Autores principales: | Kerns, Michelle, DePianto, Daryle, Yamamoto, Masayuki, Coulombe, Pierre A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993737/ https://www.ncbi.nlm.nih.gov/pubmed/20926689 http://dx.doi.org/10.1091/mbc.E10-02-0153 |
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