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The Roles of Two Distinct Regions of PINCH-1 in the Regulation of Cell Attachment and Spreading
Cells attach to the extracellular matrix (ECM) through integrins to form focal adhesion complexes, and this process is followed by the extension of lamellipodia to enable cell spreading. PINCH-1, an adaptor protein essential for the regulation of cell–ECM adhesion, consists of five tandem LIM domain...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993741/ https://www.ncbi.nlm.nih.gov/pubmed/20926685 http://dx.doi.org/10.1091/mbc.E10-05-0459 |