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The Roles of Two Distinct Regions of PINCH-1 in the Regulation of Cell Attachment and Spreading

Cells attach to the extracellular matrix (ECM) through integrins to form focal adhesion complexes, and this process is followed by the extension of lamellipodia to enable cell spreading. PINCH-1, an adaptor protein essential for the regulation of cell–ECM adhesion, consists of five tandem LIM domain...

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Detalles Bibliográficos
Autores principales: Ito, Satoko, Takahara, Yuko, Hyodo, Toshinori, Hasegawa, Hitoki, Asano, Eri, Hamaguchi, Michinari, Senga, Takeshi
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993741/
https://www.ncbi.nlm.nih.gov/pubmed/20926685
http://dx.doi.org/10.1091/mbc.E10-05-0459