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Rubicon and PLEKHM1 Negatively Regulate the Endocytic/Autophagic Pathway via a Novel Rab7-binding Domain

The endocytic and autophagic pathways are involved in the membrane trafficking of exogenous and endogenous materials to lysosomes. However, the mechanisms that regulate these pathways are largely unknown. We previously reported that Rubicon, a Beclin 1–binding protein, negatively regulates both the...

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Detalles Bibliográficos
Autores principales: Tabata, Keisuke, Matsunaga, Kohichi, Sakane, Ayuko, Sasaki, Takuya, Noda, Takeshi, Yoshimori, Tamotsu
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993745/
https://www.ncbi.nlm.nih.gov/pubmed/20943950
http://dx.doi.org/10.1091/mbc.E10-06-0495