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Nuclear Organization and Dynamics of 7SK RNA in Regulating Gene Expression

Noncoding RNAs play important roles in various aspects of gene regulation. We have identified 7SK RNA to be enriched in nuclear speckles or interchromatin granule clusters (IGCs), a subnuclear domain enriched in pre-mRNA processing factors. 7SK RNA, in association with HEXIM 1 and 2, is involved in...

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Detalles Bibliográficos
Autores principales: Prasanth, Kannanganattu V., Camiolo, Matthew, Chan, Grace, Tripathi, Vidisha, Denis, Laurence, Nakamura, Tetsuya, Hübner, Michael R., Spector, David L.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993747/
https://www.ncbi.nlm.nih.gov/pubmed/20881057
http://dx.doi.org/10.1091/mbc.E10-02-0105