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Inner/Outer Nuclear Membrane Fusion in Nuclear Pore Assembly: Biochemical Demonstration and Molecular Analysis

Nuclear pore complexes (NPCs) are large proteinaceous channels embedded in double nuclear membranes, which carry out nucleocytoplasmic exchange. The mechanism of nuclear pore assembly involves a unique challenge, as it requires creation of a long-lived membrane-lined channel connecting the inner and...

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Detalles Bibliográficos
Autores principales: Fichtman, Boris, Ramos, Corinne, Rasala, Beth, Harel, Amnon, Forbes, Douglass J.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993748/
https://www.ncbi.nlm.nih.gov/pubmed/20926687
http://dx.doi.org/10.1091/mbc.E10-04-0309