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RRP1B Targets PP1 to Mammalian Cell Nucleoli and Is Associated with Pre-60S Ribosomal Subunits

A pool of protein phosphatase 1 (PP1) accumulates within nucleoli and accounts for a large fraction of the serine/threonine protein phosphatase activity in this subnuclear structure. Using a combination of fluorescence imaging with quantitative proteomics, we mapped the subnuclear localization of th...

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Detalles Bibliográficos
Autores principales: Chamousset, Delphine, De Wever, Veerle, Moorhead, Greg B., Chen, Yan, Boisvert, Francois-Michel, Lamond, Angus I., Trinkle-Mulcahy, Laura
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993749/
https://www.ncbi.nlm.nih.gov/pubmed/20926688
http://dx.doi.org/10.1091/mbc.E10-04-0287