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Vav3 Is Involved in GABAergic Axon Guidance Events Important for the Proper Function of Brainstem Neurons Controlling Cardiovascular, Respiratory, and Renal Parameters

Vav3 is a phosphorylation-dependent activator of Rho/Rac GTPases that has been implicated in hematopoietic, bone, cerebellar, and cardiovascular roles. Consistent with the latter function, Vav3-deficient mice develop hypertension, tachycardia, and renocardiovascular dysfunctions. The cause of those...

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Detalles Bibliográficos
Autores principales: Sauzeau, Vincent, Horta-Junior, José A. C., Riolobos, Adelaida S., Fernández, Gloria, Sevilla, María A., López, Dolores E., Montero, María J., Rico, Beatriz, Bustelo, Xosé R.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993752/
https://www.ncbi.nlm.nih.gov/pubmed/20926682
http://dx.doi.org/10.1091/mbc.E10-07-0639