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Vav3 Is Involved in GABAergic Axon Guidance Events Important for the Proper Function of Brainstem Neurons Controlling Cardiovascular, Respiratory, and Renal Parameters
Vav3 is a phosphorylation-dependent activator of Rho/Rac GTPases that has been implicated in hematopoietic, bone, cerebellar, and cardiovascular roles. Consistent with the latter function, Vav3-deficient mice develop hypertension, tachycardia, and renocardiovascular dysfunctions. The cause of those...
Autores principales: | Sauzeau, Vincent, Horta-Junior, José A. C., Riolobos, Adelaida S., Fernández, Gloria, Sevilla, María A., López, Dolores E., Montero, María J., Rico, Beatriz, Bustelo, Xosé R. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993752/ https://www.ncbi.nlm.nih.gov/pubmed/20926682 http://dx.doi.org/10.1091/mbc.E10-07-0639 |
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