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Cell Death or Survival Promoted by Alternative Isoforms of ErbB4

The significance of ErbB4 in tumor biology is poorly understood. The ERBB4 gene is alternatively spliced producing juxtamembrane (JM-a and JM-b) and cytoplasmic (CYT-1 and CYT-2) isoforms. Here, signaling via the two alternative ErbB4 JM isoforms (JM-a CYT-2 and JM-b CYT-2) was compared. Fibroblasts...

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Detalles Bibliográficos
Autores principales: Sundvall, Maria, Veikkolainen, Ville, Kurppa, Kari, Salah, Zaidoun, Tvorogov, Denis, van Zoelen, E. Joop, Aqeilan, Rami, Elenius, Klaus
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993754/
https://www.ncbi.nlm.nih.gov/pubmed/20943952
http://dx.doi.org/10.1091/mbc.E10-04-0332