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Trichostatin A accentuates doxorubicin-induced hypertrophy in cardiac myocytes

Histone deacetylase inhibitors represent a new class of anticancer therapeutics and the expectation is that they will be most effective when used in combination with conventional cancer therapies, such as the anthracycline, doxorubicin. The dose-limiting side effect of doxorubicin is severe cardioto...

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Detalles Bibliográficos
Autores principales: Karagiannis, Tom C, Lin, Ann JE, Ververis, Katherine, Chang, Lisa, Tang, Michelle M, Okabe, Jun, El-Osta, Assam
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993796/
https://www.ncbi.nlm.nih.gov/pubmed/20930262